It has been two years since Minakata Jin went back in time to the closing days of the Tokugawa shogunate. One day, Sakamoto Ryoma arrives from Kyoto to seek Jin's help. Ryoma says Katsu Kaishu's mentor, Sakuma Shozan, has been attacked by a group of samurai warriors called the Shinsengumi and is near death. However, Sakuma survives because of Jin's fervent treatment. As a troubled Jin worries that his treatments may change the course of history, Sakuma tells him, "Save people without hesitation!" After that, Jin, who had been treating the injuries of the people, was taken away by the Shinsengumi and asked to give Saigo Kichinosuke (later known as Saigo Takamori) medical attention.